Lymphoid Structures | Immunology | Topic 5

This Section Include:

  • Introduction to Major Histocompatibility Complexes (MHC)
  • MHC I and MHC II: Encoding by HLA Genes and Their Functions
  • Antigen Presentation: How MHC Proteins Present Antigen Fragments to T Cells
  • Components of MHC I: HLAA, B, and C Loci
  • MHC I Function: Binding to TCR and CD8 Receptors, Antigen Loading
  • Associated Proteins: Beta2 Microglobulins
  • Components of MHC II: HLADP, HLADQ, and HLADR Loci
  • MHC II Function: Binding to TCR and CD4, Antigen Presentation
  • Associated Proteins: Invariant Chain
  • HLA Subtypes and Associated Diseases